Das Team der Entwickungsgenetik
Dr. Katja Kapp
Wissenschaftliche Mitarbeiterin
- Telefon
- +49 561 804-4324
- Fax
- +49 561 804-4057
- k.kapp[at]uni-kassel[dot]de
- Standort
- Heinrich-Plett-Str. 40
34132 Kassel
- Raum
- IBC 1200
- Sprechstunde
Nach Vereinbarung.
Publikationen
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Clemente, G.D., Hannaford, M.R., Beati, S.A.H., Kapp, K., Januschke, J., Griffis, E.R., Müller, H.-A., 2018. Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila. Journal of Developmental Biology 6, 9. https://doi.org/10.3390/jdb6020009 https://forschung.uni-kassel.de/converis/portal/detail/Publication/51819986 |
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Spannl, S., Kumichel, A., Hebbar, S., Kapp, K., Gonzalez-Gaitan, M., Winkler, S., Blawid, R., Jessberger, G., Knust, E., 2017. The Crumbs C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration. Biology Open 6, 165–175. https://doi.org/10.1242/bio.020040 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788576 |
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Kumichel, A., Kapp, K., Knust, E., 2015. A Conserved Di-Basic Motif of Drosophila Crumbs Contributes to Efficient ER Export. Traffic (Copenhagen, Denmark) 16, 604–616. https://doi.org/10.1111/tra.12273 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789061 |
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Kapp, K., Siemens, J., Häring, H.-U., Lammers, R., 2012. Proteolytic processing of the protein tyrosine phosphatase extgreeka extracellular domain is mediated by ADAM17/TACE. European Journal of Cell Biology 91, 687–693. https://doi.org/10.1016/j.ejcb.2012.04.003 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789367 |
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Stjepanovic, G., Kapp, K., Bange, G., Graf, C., Parlitz, R., Wild, K., Mayer, M., Sinning, I., 2011. Lipids trigger a conformational switch that regulates signal recognition particle (SRP)-mediated protein targeting. Journal of Biological Physics and Chemistry 286, 23489–23497. https://doi.org/10.1074/jbc.M110.212340 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788398 |
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Kilic, A., Klose, S., Dobberstein, B., Knust, E., Kapp, K., 2010. The Drosophila Crumbs signal peptide is unusually long and is a substrate for signal peptide peptidase. European Journal of Cell Biology 89, 449–461. https://doi.org/10.1016/j.ejcb.2010.02.001 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789213 |
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Schrul, B., Kapp, K., Sinning, I., Dobberstein, B., 2010. Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes. The Biochemical journal 427, 523–534. https://doi.org/10.1042/BJ20091005 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788729 |
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Bleyer, A.J., Zivná, M., Hulková, H., Hodanová, K., Vyletal, P., Sikora, J., Zivný, J., Sovová, J., Hart, T.C., Adams, J.N., Elleder, M., Kapp, K., Haws, R., Cornell, L.D., Kmoch, S., Hart, P.S., 2010. Clinical and molecular characterization of a family with a dominant renin gene mutation and response to treatment with fludrocortisone. Clinical nephrology 74, 411–422. https://doi.org/10.5414/CNP74411 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67787882 |
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Kapp, K., Schrempf, S., Lemberg, M.K., Dobberstein, B., 2009. Post-Targeting Functions of Signal Peptides, in: Zimmermann, R. (Hrsg.), Protein Transport into the Endoplasmic Reticulum. CRC Press, London, S. 1–16. https://forschung.uni-kassel.de/converis/portal/detail/Publication/74461071 |
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Zivná, M., Matignon, M., Hodanová, K., Vylet’al, P., Kalbácová, M., Baresová, V., Sikora, J., Blazková, H., Zivný, J., Ivánek, R., Stránecký, V., Sovová, J., Claes, K., Lerut, E., Fryns, J.-P., Hart, P.S., Hart, T., Adams, J., Pawtowski, A., Clemessy, M., Gasc, J.-M., Gübler, M.-C., Antignac, C., Elleder, M., Kapp, K., Grimbert, P., Bleyer, A., Kmoch, S., 2009. Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure. American Journal of Human Genetics 85, 204–213. https://doi.org/10.1016/j.ajhg.2009.07.010 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790871 |
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Dultz, E., Hildenbeutel, M., Martoglio, B., Hochman, J., Dobberstein, B., Kapp, K., 2008. The signal peptide of the mouse mammary tumor virus Rem protein is released from the endoplasmic reticulum membrane and accumulates in nucleoli. Journal of Biological Physics and Chemistry 283, 9966–9976. https://doi.org/10.1074/jbc.M705712200 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790567 |
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Kapp, K., Siemens, J., Weyrich, P., Schulz, J., Häring, H.-U., Lammers, R., 2007. Extracellular domain splice variants of a transforming protein tyrosine phosphatase alpha mutant differentially activate Src-kinase dependent focus formation. Genes to Cells 12, 63–73. https://doi.org/10.1111/j.1365-2443.2006.01034.x https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789546 |
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Lundin, C., Käll, L., Kreher, S., Kapp, K., Sonnhammer, E., Carlson, J., Heijne, G., Nilsson, I., 2007. Membrane topology of the Drosophila OR83b odorant receptor. FEBS Letters 581, 5601–5604. https://doi.org/10.1016/j.febslet.2007.11.007 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788882 |
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Hennige, A., Stefan, N., Kapp, K., Lehmann, R., Weigert, C., Beck, A., Moeschel, K., Mushack, J., Schleicher, E., Häring, H.-U., 2006. Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20, 1206–1208. https://doi.org/10.1096/fj.05-4635fje https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790415 |
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Weyrich, P., Kapp, K., Niederfellner, G., Melzer, M., Lehmann, R., Häring, H.-U., Lammers, R., 2004. Partitioning-defective protein 6 regulates insulin-dependent glycogen synthesis via atypical protein kinase C. Molecular endocrinology (Baltimore, Md.) 18, 1287–1300. https://doi.org/10.1210/me.2003-0253 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788236 |
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Kapp, K., Knobloch, J., Schüssler, P., Sroka, S., Lammers, R., Kunz, W., Grevelding, C., 2004. The Schistosoma mansoni Src kinase TK3 is expressed in the gonads and likely involved in cytoskeletal organization. Molecular and biochemical parasitology 138, 171–182. https://doi.org/10.1016/j.molbiopara.2004.07.010 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790083 |
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Kapp, K., Coustau, C., Wippersteg, V., Jourdane, J., Kunz, W., Grevelding, C., 2003. Transplantation of in vitro-generated Schistosoma mansoni mother sporocysts into Biomphalaria glabrata. Parasitology Research 91, 482–485. https://doi.org/10.1007/s00436-003-0951-1 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790236 |
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Kapp, K., Metzinger, E., Kellerer, M., Häring, H.-U., Lammers, R., 2003. The protein tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells. Biochemical and biophysical research communications 311, 361–364. https://doi.org/10.1016/j.bbrc.2003.10.011 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789904 |
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Kapp, K., Wippersteg, V., Kunz, W., Jackstadt, W.P., Zahner, H., Grevelding, C., 2002. HSP70-controlled GFP expression in transiently transformed schistosomes☆. Molecular and biochemical parasitology 120, 141–150. https://doi.org/10.1016/S0166-6851(01)00446-7 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790719 |
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Wippersteg, V., Kapp, K., Kunz, W., Grevelding, C., 2002. Characterisation of the cysteine protease ER60 in transgenic Schistosoma mansoni larvae. International Journal for Parasitology 32, 1219–1224. https://doi.org/10.1016/S0020-7519(02)00092-9 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788060 |
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Kapp, K., Schüssler, P., Kunz, W., Grevelding, C.G., 2001. Identification, isolation and characterization of a Fyn-like tyrosine kinase from Schistosoma mansoni. Parasitology 122, 317–327. https://doi.org/10.1017/S0031182001007430 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789725 |