Dr. Lars Hering
Postdoc
| Tel.: | +49 561 804-4083 |
| Fax: | +49 561 804-4800 |
| E-Mail: | lars.hering[at]uni-kassel.de |
Graduierung
2020 Promotion zum Dr. rer. nat., Universität Kassel, Deutschland
2010 Master of Science Biologie (M.Sc.), Universität Leipzig, Deutschland
2008 Bachelor of Science Biologie (B.Sc.), Universität Leipzig, Deutschland
Weiterbildung
2012 Teilnahme am Kurs "Programming for Evolutionary Biology", Leipzig, Deutschland
Forschungsthema: Evolution des Sehens bei den Panarthropoda
Die Fähigkeit, Licht wahrzunehmen und visuelle Informationen zu verarbeiten, ist im Tierreich weit verbreitet. Dafür sind spezielle Proteine, die Opsine, von entscheidender Bedeutung, da sie die Grundlage für die Signalkaskade zur Informationsübertragung des visuellen Reizes bilden. Um die Evolution dieser Proteine und damit auch die Entstehung des Farbsehens bei den Gliederfüßern (Arthropoda) zu verstehen, untersuche ich die Opsin-Gene bei ihren nächsten Verwandten, den Stummelfüßern (Onychophora) und Bärtierchen (Tardigrada). In Kooperation mit der Lund Vision Group (Universität Lund, Schweden) analysieren wir außerdem mit Hilfe von Verhaltensexperimenten sowie anatomischen und elektrophysiologischen Methoden die visuellen Eigenschaften der Onychophoren-Augen, um Rückschlüsse auf die Evolution des Sehens bei den Panarthropoda (Onychophora + Tardigrada + Arthropoda) ziehen zu können.
Publikationen
Hu, Z., Baer, A., Hering, L., Oliveira, I.S., Brown, D.C., Guo, X., Perrin, Q.M., Sobota, R.M., Hoon, S., Mayer, G., Harrington, M.J., & Miserez, A. (preprint): Receptor-based protein binding in the supramolecular network of velvet worm slime. bioRxiv.
Duta, S., Hering, L., Grollmann, M.M., Metzendorf, N., Gross, V., Arakawa, K., Neupert, S., Stengl, M., Herberg, F.W. & Mayer, G. (preprint): Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades. bioRxiv.
Poulhazan, A.*, Baer, A.*, Daliaho, G., Mentink-Vigier, F., Arnold, A.A., Browne, D.C., Hering, L., Archer-Hartmann, S., Pepi, L.E., Azadi, P., Schmidt, S., Mayer, G., Marcotte, I. & Harrington, M.J. (in press): Peculiar phosphonate modifications of velvet worm slime revealed by advanced nuclear magnetic resonance and mass spectrometry. Journal of the American Chemical Society. *Equal contribution.
Martin, C., Hering, L., Metzendorf, N., Hormann, S., Kasten, S., Fuhrmann, S., Werckenthin, A., Herberg, F.W., Stengl, M. & Mayer, G. (2020): Analysis of pigment-dispersing factor neuropeptides and their receptor in a velvet worm. Frontiers in Endocrinology. 11:273.
Petersen, M., Armisen, D., Gibbs, R.A., Hering, L., Khila, A., Mayer, G., Richards, S. & Misof, B. (2019): Diversity and evolution of the transposable element repertoire in arthropods with particular reference to insects. BMC Evolutionary Biology 19:11.
Treffkorn, S., Kahnke, L., Hering, L. & Mayer, G. (in press): Expression of NK cluster genes in the onychophoran Euperipatoides rowelli: Implications for the evolution of NK family genes in nephrozoans. EvoDevo.
Martin, C., Gross, V., Hering, L., Tepper, B., Jahn, H., Oliveira, I.S., Stevenson, P.A. & Mayer, G. (2017): The nervous and visual systems of onychophorans and tardigrades: learning about arthropod evolution from their closest relatives. Journal of Comparative Physiology A 203: 565–590.
Richter, S., Helm, C., Meunier, F.A., Hering, L., Campbell, L.I., Drukewitz, S.H., Undheim, E.A.B., Jenner, R.A., Schiavo, G. & Bleidorn, C. (2017): Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system. BMC Evolutionary Biology 17: 64.
Pauli, T., Vedder, L., Dowling, D., Petersen, M., Meusemann, K., Donath, A., Peters, R.S., Podsiadlowski, L., Mayer, C., Liu, S., Zhou, X., Heger, P., Wiehe, T., Hering, L., Mayer, G., Misof, B. & Niehuis, O. (2016): Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects. BMC Genomics 17: 861.
Schumann, I., Hering, L. & Mayer, G. (2016): Immunolocalization of arthropsin in the onychophoran Euperipatoides rowelli (Peripatopsidae). Frontiers in Neuroanatomy 10: 80.
Hering, L.*, Bouameur, J.-E.*, Reichelt, J.*, Magin, T. M., & Mayer, G. (2016): Novel origin of lamin-derived cytoplasmic intermediate filaments in tardigrades. eLife 5: e11117. *Shared first authorship.
Mayer, G., Hering, L., Stosch, J.M., Stevenson, P.A. & Dircksen, H. (2015): Evolution of pigment-dispersing factor neuropeptides in Panarthropoda: Insights from Onychophora (velvet worms) and Tardigrada (water bears). Journal of Comparative Neurology 523: 1865–1885.
Beckmann, H., Hering, L., Henze, M.J., Kelber, A., Stevenson, P.A. & Mayer, G. (2015): Spectral sensitivity in Onychophora (velvet worms) revealed by electroretinograms, phototactic behaviour and opsin gene expression. Journal of Experimental Biology 218: 915–922.
Franke, F.A., Schumann, I., Hering, L. & Mayer, G. (2015): Phylogenetic analysis and expression patterns of Pax genes in the onychophoran Euperipatoides rowelli reveal a novel bilaterian Pax subfamily. Evolution & Development 17: 3–20.
Richter, S., Schwarz, F., Hering, L., Böggemann, M., & Bleidorn, C. (2015): The utility of genome skimming for phylogenomic analyses as demonstrated for glycerid relationships (Annelida, Glyceridae). Genome Biology and Evolution 7(12): 3443–3462.
Hering, L. & Mayer, G. (2014): Analysis of the opsin repertoire in the tardigrade Hypsibius dujardini provides insights into the evolution of opsin genes in Panarthropoda. Genome Biology and Evolution 6: 2380–2391.
von Reumont, B.M., Campbell, L.I., Richter, S., Hering, L., Sykes, D., Hetmank, J., Jenner, R.A. & Bleidorn, C. (2014): A polychaete's powerful punch: venom gland transcriptomics of Glycera reveals a complex cocktail of toxin homologs. Genome Biology and Evolution 6: 2406–2423.
Struck, T.H., Wey-Fabrizius, A.R., Golombek, A., Hering, L., Weigert, A., Bleidorn, C., Klebow, S., Iakovenko, N., Hausdorf, B., Petersen, M., Kück, P., Herlyn, H. & Hankeln, T. (2014): Platyzoan paraphyly based on phylogenomic data supports a non-coelomate ancestry of Spiralia. Molecular Biology and Evolution 31: 1833–1849.
Oliveira, I.S., Franke, F.A., Hering, L., Schaffer, S., Rowell, D.M., Weck-Heimann, A., Monge-Nájera, J., Morera-Brenes, B. & Mayer, G. (2012): Unexplored character diversity in Onychophora (velvet worms): a comparative study of three peripatid species. PLOS ONE 7(12): e51220.
Hering, L., Henze, M.J., Kohler, M., Kelber, A., Bleidorn, C., Leschke, M., Nickel, B., Meyer, M., Kircher, M., Sunnucks, P. & Mayer, G. (2012): Opsins in Onychophora (velvet worms) suggest a single origin and subsequent diversification of visual pigments in arthropods. Molecular Biology and Evolution 29: 3451–3458.
Vorträge
Analysis of the opsin repertoire in the tardigrade Hypsibius dujardini – insights into the evolution of opsin genes in Panarthropoda and Bilateria; 107. Jahrestagung der Deutschen Zoologischen Gesellschaft (DZG) 2014, Göttingen, Deutschland.
Onychophora – a key group for understanding the evolution of arthropods; Programming for Evolutionary Biology Course 2012, Leipzig, Deutschland.
Opsins in Onychophora (velvet worms) suggest a single origin and subsequent diversification of visual pigments in arthropods; 13. Jahrestagung der Gesellschaft für Biologische Systematik (GfBS) 2012, Bonn, Deutschland.
Poster
Unexpected diversity of opsin genes in the tardigrade Hypsibius dujardini – insights into the photosensitive system in the last common ancestor of Panarthropoda. 15. Jahrestagung der Gesellschaft für Biologische Systematik (GfBS) 2014, Dresden, Deutschland.
Transcriptome analyses in Onychophora suggest two pigment-dispersing factor genes in the last common ancestor of Panarthropoda. 106. Jahrestagung der Deutschen Zoologischen Gesellschaft (DZG) 2013, München, Deutschland.
Transcriptome analyses in representatives of Tardigrada and Onychophora suggest that colour vision evolved in arthropods; 2nd BioSyst.EU meeting 2013, Wien, Österreich.
Opsins in Onychophora (velvet worms) suggest a single origin and subsequent diversification of visual pigments in arthropods; Graduiertentreffen DZG – Fachgruppe Zoologische Systematik 2012, Leipzig, Deutschland.
Evolution of colour vision in Panarthropoda: Insights from opsin genes in Onychophora and Tardigrada; 105. Jahrestagung der Deutschen Zoologischen Gesellschaft (DZG) 2012, Konstanz, Deutschland. Preis für das beste Poster der Fachgruppe "Zoologische Systematik".