Proteins involved in endocytic transit (Coronin pg.1)

Protein Text

Top: Coronin (red dots) in particle uptake, degradation, and exocytosis phases.

Right: Coronin-GFP (green) accumulates at the site of phagocytic uptake (red particle). (A click on the frame will start the movie).

Protein Text 2

Function: A mutant lacking coronin has a reduced efficiency of phagocytosis.

Reference:

Maniak et al., 1995

  • Maniak, M., Rauchenberger, R., Albrecht, R., Murphy, J. & Gerisch, G.: Coronin involved in phagocytosis: dynamics of particle-induced relocalization visualized by a green fluorescent protein tag. Cell 83, 915-924, 1995

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