Research associate (EG 13 TV-H) - in the field of biophysics

Part-time with half of the regular working time of a full-time employee. The position is initially limited for 1 year with the possibility of extension within the project "Insertion and folding of beta-barrel membrane proteins in lipid bilayers - functions of BamA (YaeT) and membrane-anchored BAM proteins on the folding of integral membrane proteins" (§ 2 Abs. 1 WissZeitVG). The possibility to do a PhD is given.

Tasks:

Research on the incorporation of proteins into membranes as well as protein-protein interactions on model membranes; research on methods and principles of folding and incorporation of membrane proteins, spectroscopy, protein expression and purification, site-directed mutagenesis, membrane proteins as well as biomimetic membranes.

The methodological focus of the department of biophysics is on:

• Preparation of mutants of membrane proteins from bacteria or eukaryotic cell organelles, protein expression and isolation from cells using chromatographic methods.
• Preparation of lipid model membranes and proteoliposomes
• Investigation of protein-protein and protein-lipid interactions
• Investigation of membrane properties and functions
• Spectroscopy (fluorescence, ESR (EPR), CD spectroscopy)
• Structure/functional relationships of proteins
• Kinetics and thermodynamics of biomolecular structural changes and interactions

Modern laboratories and software equipment are available for all areas to perform experimental work and analyze the results.

Prerequisites:

• University scientific degree in biochemistry or biophysics completed with at least good grades.
• experience with molecular biology, expression and purification of proteins
• Experience with biophysical methods

Advantageous are:

• good knowledge of English
• thorough and independent working methods
• a high degree of organizational skills
• experience in protein spectroscopy

For further inquiries please contact Prof. Dr. Jörg H. Kleinschmidt, Tel.: 0561-804-4041, E-Mail: jhk@uni-kassel.de.

The protection of your personal data is important to us, therefore we will handle your personal data with care. If you give us your data, you thereby allow us to store and use it in accordance with the Hessian Data Protection and Freedom of Information Act. You can object to this at any time. Your personal data will then be deleted.

In the interest of equal opportunity, the University of Kassel strives to offer women and men the same development opportunities and to counteract existing disadvantages. The aim is to significantly increase the proportion of women in research and teaching. Qualified women are therefore expressly encouraged to apply. Severely disabled applicants will be given preference if they are equally qualified and qualified. Full-time positions are generally divisible. Please submit only copies of your application documents (no folders), as these cannot be returned after the selection process has been completed; they will be destroyed in compliance with data protection regulations. Applications with informative documents should be sent to the President of the University of Kassel, 34109 Kassel or bewerbungen[at]uni-kassel[dot]de, quoting the reference number, and preferably also in electronic form.