Research Assistant (EG 13 TV-H) - Department of Biophysics

Part-time with half the regular working hours of a full-time employee. The position is initially limited for 1 year with the possibility of extension within the framework of the project "Insertion and folding of beta-barrel membrane proteins in lipid bilayers - functions of BamA (YaeT) and membrane-anchored BAM proteins on the folding of integral membrane proteins" (§ 2 para. 1 WissZeitVG). The possibility of a doctorate is given.

Tasks:

Research on the incorporation of proteins into membranes and on protein-protein interactions on model membranes; research on methods and principles of folding and incorporation of membrane proteins, spectroscopy, protein expression and purification, site-directed mutagenesis, membrane proteins and biomimetic membranes.

The methodological focus of the Biophysics Department is on

• Preparation of mutants of membrane proteins from bacteria or eukaryotic cell organelles, protein expression and isolation from cells using chromatographic methods
• Production of lipid model membranes and proteoliposomes
• Investigation of protein-protein and protein-lipid interactions
• Investigation of membrane properties and functions
• Spectroscopy (fluorescence, ESR (EPR), CD spectroscopy)
• Structure/functional relationships of proteins
• Kinetics and thermodynamics of biomolecular structural changes and interactions

Modern laboratories and software equipment for carrying out experimental work and analyzing the results are available for all areas.

Prerequisites:

• University degree in biochemistry or biophysics with at least a good grade
• Experience with molecular biology, expression and purification of proteins
• Experience with biophysical methods

Advantageous are:

• good knowledge of English
• Thorough and independent working methods
• a high degree of organizational skills
• experience in the spectroscopy of proteins

If you have any questions, please contact Prof. Dr. Jörg H. Kleinschmidt, phone: 0561-804-4041, e-mail: jhk@uni-kassel.de.

The protection of your personal data is important to us, which is why we will handle your personal data with care. If you provide us with your data, you authorize us to store and use it in accordance with the Hessian Data Protection and Freedom of Information Act. You can object to this at any time

In the interests of equal opportunities, the University of Kassel endeavors to offer women and men the same development opportunities and to counteract existing disadvantages. The aim is to significantly increase the proportion of women in research and teaching. Qualified women are therefore expressly encouraged to apply. Severely disabled applicants with equal aptitude and qualifications will be given preference. Full-time positions are generally divisible. Please only send us copies of your application documents (no folders), as these cannot be returned after the selection process has been completed; they will be destroyed in accordance with data protection regulations. Applications with informative documents should be sent to the President of the University of Kassel, 34109 Kassel or bewerbungen[at]uni-kassel[dot]de, quoting the reference number, also in electronic form.