Research Assistant (m/f/d), EG 13 TV-H - Department of Biophysics

Part-time with half the regular working hours of a full-time employee. The position is initially limited until 30.06.2021 as part of the project "Insertion and folding of beta-barrel membrane proteins in lipid bilayers - functions of BamA (YaeT) and membrane-anchored BAM proteins on the folding of integral membrane proteins" (§ 2 Abs. 2 WissZeitVG). The possibility of a doctorate is given.

Tasks:

Research on the incorporation of proteins into membranes and on protein-protein interactions on model membranes; methods and principles of folding and incorporation of membrane proteins, spectroscopy, protein expression and purification, site-directed mutagenesis, membrane proteins; biomimetic membranes.

The methodological focus of the Biophysics Department is on

• Studies on the incorporation and folding of membrane proteins in model membranes
• Preparation of mutants of membrane proteins from bacteria or eukaryotic cell organelles, protein expression and isolation from cells using chromatographic methods
• Production of lipid model membranes and proteoliposomes
• Investigation of protein-protein and protein-lipid interactions
• Investigation of membrane properties and functions
• Spectroscopy (fluorescence, ESR (EPR), CD spectroscopy)
• Structure/functional relationships of proteins
• Kinetics and thermodynamics of biomolecular structural changes and interactions

Modern laboratories and software equipment for carrying out experimental work and analyzing the results are available for all areas.

Prerequisites:

• University degree with very good or good results and an experimental thesis
• Experience with studies on proteins or in spectroscopy
• Thorough and independent way of working
• Good organizational skills

Advantageous are:

• Good knowledge of English
• Experience with the purification of proteins
• Experience in molecular biology, e.g. expression of proteins
• Experience with biophysical methods, especially spectroscopic methods

If you have any questions, please contact Prof. Dr. Jörg H. Kleinschmidt, phone: 0561-804-4041, e-mail: jhk[at]uni-kassel[dot]de.

The protection of your personal data is important to us, which is why we will handle your personal data with care. If you provide us with your data, you authorize us to store and use it in accordance with the Hessian Data Protection and Freedom of Information Act. You can object to this at any time. Your personal data will then be deleted. Information in accordance with Art. 13 GDPR for the application procedure at the University of Kassel can be found at www.uni-kassel.de/go/ausschreibung-datenschutz

In the interests of equal opportunities, the University of Kassel endeavors to offer women and men the same development opportunities and to counteract existing disadvantages. The aim is to significantly increase the proportion of women in research and teaching. Qualified women are therefore expressly encouraged to apply. Severely disabled applicants with equal aptitude and qualifications will be given preference. Full-time positions are generally divisible. Please only send us copies of your application documents (no folders), as these cannot be returned after the selection process has been completed; they will be destroyed in accordance with data protection regulations. Applications with informative documents should be sent to the President of the University of Kassel, 34109 Kassel or bewerbungen[at]uni-kassel[dot]de, stating the reference number in the subject line, also in electronic form.